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Select item 97251161.

Updates on Juvenile Dermatomyositis from the Last Decade: Classification to Outcomes

Hanna Kim, Adam M. Huber, Susan Kim

Rheum Dis Clin North Am. Author manuscript; available in PMC 2022 Dec 6.

Published in final edited form as: Rheum Dis Clin North Am. 2021 Nov; 47(4): 669–690. Published online 2021 Sep 2. doi: 10.1016/j.rdc.2021.07.003

PMCID:: PMC9725116

Article PDF–763K

Select item 63054192.

Systemic and Tissue Inflammation in Juvenile Dermatomyositis: From Pathogenesis to the Quest for Monitoring Tools

Judith Wienke, Claire T. Deakin, Lucy R. Wedderburn, Femke van Wijk, Annet van Royen-Kerkhof

Front Immunol. 2018; 9: 2951. Published online 2018 Dec 18. doi: 10.3389/fimmu.2018.02951

PMCID:: PMC6305419

Article PDF–1.5M

Select item 41135993.

Developing a provisional, international Minimal Dataset for Juvenile Dermatomyositis: for use in clinical practice to inform research

Liza J McCann, Katie Arnold, Clarissa A Pilkington, Adam M Huber, Angelo Ravelli, Laura Beard, Michael W Beresford, Lucy R Wedderburn

Pediatr Rheumatol Online J. 2014; 12: 31. Published online 2014 Jul 21. doi: 10.1186/1546-0096-12-31

PMCID:: PMC4113599

Article PDF–428K

Select item 42271274.

Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study

Sarah L Tansley, Zoe E Betteridge, Harsha Gunawardena, Thomas S Jacques, Catherine M Owens, Clarissa Pilkington, Katie Arnold, Shireena Yasin, Elena Moraitis, Lucy R Wedderburn, Neil J McHugh

Arthritis Res Ther. 2014; 16(4): R138. Published online 2014 Jul 2. doi: 10.1186/ar4600

PMCID:: PMC4227127

Article PDF–214K

Select item 83369145.

Juvenile Dermatomyositis: New Clues to Diagnosis and Therapy

Lauren M. Pachman, Brian E. Nolan, Deidre DeRanieri, Amer M. Khojah

Curr Treatm Opt Rheumatol. Author manuscript; available in PMC 2021 Aug 4.

Published in final edited form as: Curr Treatm Opt Rheumatol. 2021 Mar; 7(1): 39–62. Published online 2021 Feb 6. doi: 10.1007/s40674-020-00168-5

PMCID:: PMC8336914

Article PDF–455K

Select item 41448496.

Increased Presence of FOXP3⁺ Regulatory T Cells in Inflamed Muscle of Patients with Active Juvenile Dermatomyositis Compared to Peripheral Blood

Yvonne Vercoulen, Felicitas Bellutti Enders, Jenny Meerding, Maud Plantinga, Elisabeth F. Elst, Hemlata Varsani, Christa van Schieveen, Mette H. Bakker, Mark Klein, Rianne C. Scholman, Wim Spliet, Valeria Ricotti, Hans J. P. M. Koenen, Roel A. de Weger, Lucy R. Wedderburn, Annet van Royen-Kerkhof, Berent J. Prakken

PLoS One. 2014; 9(8): e105353. Published online 2014 Aug 26. doi: 10.1371/journal.pone.0105353

PMCID:: PMC4144849

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Select item 58816027.

Advances in Juvenile Dermatomyositis: Myositis Specific Antibodies Aid in Understanding Disease Heterogeneity

Lauren M. Pachman, Amer M. Khojah

J Pediatr. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: J Pediatr. 2018 Apr; 195: 16–27. doi: 10.1016/j.jpeds.2017.12.053

PMCID:: PMC5881602

Article PDF–789K

Select item 52843518.

Consensus-based recommendations for the management of juvenile dermatomyositis

Felicitas Bellutti Enders, Brigitte Bader-Meunier, Eileen Baildam, Tamas Constantin, Pavla Dolezalova, Brian M Feldman, Pekka Lahdenne, Bo Magnusson, Kiran Nistala, Seza Ozen, Clarissa Pilkington, Angelo Ravelli, Ricardo Russo, Yosef Uziel, Marco van Brussel, Janjaap van der Net, Sebastiaan Vastert, Lucy R Wedderburn, Nicolaas Wulffraat, Liza J McCann, Annet van Royen-Kerkhof

Ann Rheum Dis. 2017 Feb; 76(2): 329–340. Published online 2016 Aug 11. doi: 10.1136/annrheumdis-2016-209247

PMCID:: PMC5284351

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Select item 69731459.

Galectin‐9 and CXCL10 as Biomarkers for Disease Activity in Juvenile Dermatomyositis: A Longitudinal Cohort Study and Multicohort Validation

Judith Wienke, Felicitas Bellutti Enders, Johan Lim, Jorre S. Mertens, Luuk L. van den Hoogen, Camiel A. Wijngaarde, Joo Guan Yeo, Alain Meyer, Henny G. Otten, Ruth D. E. Fritsch‐Stork, Sylvia S. M. Kamphuis, Esther P. A. H. Hoppenreijs, Wineke Armbrust, J. Merlijn van den Berg, Petra C. E. Hissink Muller, Janneke Tekstra, Jessica E. Hoogendijk, Claire T. Deakin, Wilco de Jager, Joël A. G. van Roon, W. Ludo van der Pol, Kiran Nistala, Clarissa Pilkington, Marianne de Visser, Thaschawee Arkachaisri, Timothy R. D. J. Radstake, Anneke J. van der Kooi, Stefan Nierkens, Lucy R. Wedderburn, Annet van Royen‐Kerkhof, Femke van Wijk

Arthritis Rheumatol. 2019 Aug; 71(8): 1377–1390. Published online 2019 Mar 12. doi: 10.1002/art.40881

PMCID:: PMC6973145

Article PDF–714K

Select item 1018464310.

Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care

Charalampia Papadopoulou, Christine Chew, Meredyth G. Ll. Wilkinson, Liza McCann, Lucy R. Wedderburn

Nat Rev Rheumatol. 2023; 19(6): 343–362. Published online 2023 May 15. doi: 10.1038/s41584-023-00967-9

PMCID:: PMC10184643

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Select item 856447611.

Dermatomyositis With Anti-MDA5 Antibodies: Bioclinical Features, Pathogenesis and Emerging Therapies

Anaïs Nombel, Nicole Fabien, Frédéric Coutant

Front Immunol. 2021; 12: 773352. Published online 2021 Oct 20. doi: 10.3389/fimmu.2021.773352

PMCID:: PMC8564476

Article PDF–11M

Select item 926308312.

Cardiovascular Abnormalities in Juvenile Dermatomyositis: A Scoping Review for the Clinical Rheumatologists

Sanjib Mondal, Prabal Barman, Pandiarajan Vignesh

Front Med (Lausanne) 2022; 9: 827539. Published online 2022 Jun 24. doi: 10.3389/fmed.2022.827539

PMCID:: PMC9263083

Article PDF–728K

Select item 601972313.

Development of practice and consensus-based strategies including a treat-to-target approach for the management of moderate and severe juvenile dermatomyositis in Germany and Austria

Claas H. Hinze, Prasad T. Oommen, Frank Dressler, Andreas Urban, Frank Weller-Heinemann, Fabian Speth, Elke Lainka, Jürgen Brunner, Heike Fesq, Dirk Foell, Wolfgang Müller-Felber, Ulrich Neudorf, Christoph Rietschel, Tobias Schwarz, Ulrike Schara, Johannes-Peter Haas

Pediatr Rheumatol Online J. 2018; 16: 40. Published online 2018 Jun 25. doi: 10.1186/s12969-018-0257-6

PMCID:: PMC6019723

Article PDF–627K

Select item 732961714.

Endothelial and Inflammation Biomarker Profiles at Diagnosis Reflecting Clinical Heterogeneity and Serving as a Prognostic Tool for Treatment Response in Two Independent Cohorts of Patients With Juvenile Dermatomyositis

Judith Wienke, Lauren M. Pachman, Gabrielle A. Morgan, Joo Guan Yeo, Maria C. Amoruso, Victoria Hans, Sylvia S. M. Kamphuis, Esther P. A. H. Hoppenreijs, Wineke Armbrust, J. Merlijn van den Berg, Petra C. E. Hissink Muller, Kyra A. Gelderman, Thaschawee Arkachaisri, Femke van Wijk, Annet van Royen‐Kerkhof

Arthritis Rheumatol. 2020 Jul; 72(7): 1214–1226. Published online 2020 May 29. doi: 10.1002/art.41236

PMCID:: PMC7329617

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Select item 618941815.

The Vasculopathy of Juvenile Dermatomyositis

Charalampia Papadopoulou, Liza J. McCann

Front Pediatr. 2018; 6: 284. Published online 2018 Oct 9. doi: 10.3389/fped.2018.00284

PMCID:: PMC6189418

Article PDF–857K

Select item 1001787316.

Calcinosis in juvenile dermatomyositis: Updates on pathogenesis and treatment

Caitlan S. Pinotti, Laura Cannon, Jeffrey A. Dvergsten, Eveline Y. Wu

Front Med (Lausanne) 2023; 10: 1155839. Published online 2023 Mar 2. doi: 10.3389/fmed.2023.1155839

PMCID:: PMC10017873

Article PDF–712K

Select item 473719917.

Analysis of Published Criteria for Clinically Inactive Disease in a Large Juvenile Dermatomyositis Cohort Shows That Skin Disease Is Underestimated

Beverley Almeida, Raquel Campanilho‐Marques, Katie Arnold, Clarissa A. Pilkington, Lucy R. Wedderburn, Kiran Nistala, on behalf of the Juvenile Dermatomyositis Research Group, Kate Armon, Vanja Briggs, Joe Ellis‐Gage, Holly Roper, Joanna Watts, Eileen Baildam, Louise Hanna, Olivia Lloyd, Liza McCann, Ian Roberts, Ann McGovern, Phil Riley, Eslam Al‐Abadi, Clive Ryder, Janis Scott, Taunton Southwood, Beverley Thomas, Tania Amin, Deborah Burton, Gillian Jackson, Vanessa Van Rooyen, Mark Wood, Sue Wyatt, Michael Browne, Joyce Davidson, Sue Ferguson, Janet Gardner‐Medwin, Neil Martin, Liz Waxman, Helen Foster, Mark Friswell, Sharmila Jandial, Lisa Qiao, Ethan Sen, Eve Smith, Vicky Stevenson, Alison Swift, Debbie Wade, Stuart Watson, Lindsay Crate, Anna Frost, Mary Jordan, Ellen Mosley, Rangaraj Satyapal, Elizabeth Stretton, Helen Venning, Kishore Warrier, Beverley Almeida, Katie Arnold, Laura Beard, Virginia Brown, Raquel Campanilho‐Marques, Elli Enayat, Yvonne Glackin, Elizabeth Halkon, Nathan Hasson, Audrey Juggins, Laura Kassoumeri, Sian Lunt, Sue Maillard, Kiran Nistala, Clarissa Pilkington, Stephanie Simou, Sally Smith, Hemlata Varsani, Lucy Wedderburn, Kevin Murray, John Ioannou, Linda Suffield, Muthana Al‐Obaidi, Sam Leach, Helen Lee, Helen Smith, Emma Inness, Eunice Kendall, David Mayers, Nick Wilkinson, Jacqui Clinch, Helen Pluess‐Hall

Arthritis Rheumatol. 2015 Sep; 67(9): 2495–2502. Published online 2015 Aug 26. doi: 10.1002/art.39200

PMCID:: PMC4737199

Article PDF–307K

Select item 601134018.

Current management of juvenile dermatomyositis in Germany and Austria: an online survey of pediatric rheumatologists and pediatric neurologists

Claas H. Hinze, Fabian Speth, Prasad T. Oommen, Johannes-Peter Haas

Pediatr Rheumatol Online J. 2018; 16: 38. Published online 2018 Jun 20. doi: 10.1186/s12969-018-0256-7

PMCID:: PMC6011340

Article PDF–754K

Select item 594763619.

Efficacy and Safety of Cyclophosphamide Treatment in Severe Juvenile Dermatomyositis Shown by Marginal Structural Modeling

Claire T. Deakin, Raquel Campanilho‐Marques, Stefania Simou, Elena Moraitis, Lucy R. Wedderburn, Eleanor Pullenayegum, Clarissa A. Pilkington, the Juvenile Dermatomyositis Research Group

Arthritis Rheumatol. 2018 May; 70(5): 785–793. Published online 2018 Mar 25. doi: 10.1002/art.40418

PMCID:: PMC5947636

Article PDF–327K

Select item 509162220.

Muscle Biopsy Findings in Combination With Myositis‐Specific Autoantibodies Aid Prediction of Outcomes in Juvenile Dermatomyositis

Claire T. Deakin, Shireena A. Yasin, Stefania Simou, Katie A. Arnold, Sarah L. Tansley, Zoe E. Betteridge, Neil J. McHugh, Hemlata Varsani, Janice L. Holton, Thomas S. Jacques, Clarissa A. Pilkington, Kiran Nistala, Lucy R. Wedderburn, on behalf of the UK Juvenile Dermatomyositis Research Group, Kate Armon, Joe Ellis‐Gage, Holly Roper, Vanja Briggs, Joanna Watts, Liza McCann, Ian Roberts, Eileen Baildam, Louise Hanna, Olivia Lloyd, Susan Wadeson, Phil Riley, Ann McGovern, Clive Ryder, Janis Scott, Beverley Thomas, Taunton Southwood, Eslam Al‐Abadi, Sue Wyatt, Gillian Jackson, Tania Amin, Mark Wood, Vanessa VanRooyen, Deborah Burton, Joyce Davidson, Janet Gardner‐Medwin, Neil Martin, Sue Ferguson, Liz Waxman, Michael Browne, Mark Friswell, Alison Swift, Sharmila Jandial, Vicky Stevenson, Debbie Wade, Ethan Sen, Eve Smith, Lisa Qiao, Stuart Watson, Claire Duong, Helen Venning, Rangaraj Satyapal, Elizabeth Stretton, Mary Jordan, Ellen Mosley, Anna Frost, Lindsay Crate, Kishore Warrier, Stefanie Stafford, Nathan Hasson, Sue Maillard, Elizabeth Halkon, Virginia Brown, Audrey Juggins, Sally Smith, Sian Lunt, Elli Enayat, Laura Kassoumeri, Laura Beard, Yvonne Glackin, Beverley Almeida, Raquel Marques, Stefanie Dowle, Charis Papadopoulou, Kevin Murray, John Ioannou, Linda Suffield, Muthana Al‐Obaidi, Helen Lee, Sam Leach, Helen Smith, Anne‐Marie McMahon, Heather Chisem, Ruth Kingshott, Nick Wilkinson, Emma Inness, Eunice Kendall, David Mayers, Ruth Etherton, Kathryn Bailey, Jacqui Clinch, Natalie Fineman, Helen Pluess‐Hall, Lindsay Vallance, Louise Akeroyd, Alice Leahy, Amy Collier, Rebecca Cutts, Hans De Graaf, Brian Davidson, Sarah Hartfree, Danny Pratt

Arthritis Rheumatol. 2016 Nov; 68(11): 2806–2816. Published online 2016 Oct 9. doi: 10.1002/art.39753

PMCID:: PMC5091622

Article PDF–279K

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PMC Images search for juvenile dermatomyositis

FIGURE 1

Pathogenesis of cardiovascular complications in children with juvenile dermatomyositis (JDM).

Cardiovascular Abnormalities in Juvenile Dermatomyositis: A Scoping Review for the Clinical Rheumatologists

Front Med (Lausanne). 2022;9:827539.
Fig. 2

Juvenile dermatomyositis: skeletal muscle biopsy with characteristic perivascular mononuclear cell infiltrate (HE, x400)

Juvenile dermatomyositis in a 14-year old Nigerian girl

Arch Clin Cases. 2020;7(1):5-9.
Fig. 1

Capillaroscopy of patients with active, pure dermatomyositis in power of 250× showing lowered density (6 capillary/mm), presence of giant loops, hairpin capillaries, and haemorrhages compatible with active scleroderma pattern of capillaroscopy (A), overlap myositis (anti-Jo-1 syndrome with dermatomyositis features) showing lowered density (6 capillary/mm), presence of giant loops, abnormal shape capillaries and haemorrhages compatible with active scleroderma pattern of capillaroscopy (B), juvenile dermatomyositis showing lowered density (5 capillary/mm), presence of giant loops, abnormal shape capillaries and haemorrhages compatible with active scleroderma pattern of capillaroscopy (C), pure polymyositis showing normal density (9 capillary/mm), normal diameter, hairpin capillaries and no haemorrhages compatible with normal capillaroscopy (D).
DM – dermatomyositis, JDM – juvenile dermatomyositis, OM – overlap myositi , PM – polymyositis.

Nailfold capillaroscopy changes with disease activity in patients with inflammatory myositis including overlap myositis, pure dermatomyositis, and pure polymyositis

Reumatologia. 2022;60(1):42-52.
Major histocompatibility complex I and II expression in muscle fibre membrane surface of juvenile and adult dermatomyositis. Notes: The immunohistochemistry analysis demonstrates significantly higher major histocompatibility complex I expression in fibres of juvenile dermatomyositis compared to adult dermatomyositis, in contrast to major histocompatibility complex II expression.

Skeletal muscle major histocompatibility complex class I and II expression differences in adult and juvenile dermatomyositis

Clinics (Sao Paulo). 2012 Aug;67(8):885-890.